5 Surprising Benefits of IV NAD+

NAD+ is a critical molecule found in every cell of your body. When it is deficient, it can affect your aging, cognitive performance, and much more.

What is NAD+?

NAD+ is a coenzyme of vitamin B3 that is vital for healthy metabolism and healing.

#1 NAD Promotes Peak Cognitive Performance

Our cognitive performance can be decreased by multiple factors:

• Normal aging
• Cerebrovascular disease (stroke, for example)
• Metabolic dysfunction (diabetes and mitochondrial dysregulation for example)
• Trauma
• Dementia
• Reduces fatigue

NAD+ plays a critical role in our energy metabolism and reduction of oxidative stress. The normal decline in NAD+ levels with age coincides with the development of cognitive impairment from many of these conditions. Ongoing studies support the mechanism of NAD+ supporting brain health in dementia, diabetes, stroke, age-related cognitive decline, and traumatic brain injury. In fact, NAD+ supplementation appears to protect the integrity of the blood-brain barrier: the cellular barrier that protect the brain from toxins in the blood.

#2 Skin Health and Aesthetics

Our skin is our first line of defense to environmental damage. In fact, NAD+ levels decrease in the skin over time in areas where DNA damage accumulates. NAD+ supports healthy skin in many ways:

• Supporting DNA repair in damaged skin
• Promoting fibroblast health to support collagen and elastin production (possibly through SIRT1 activation)
• Counteracting the death of skin rejuvenating cells
• Decrease advanced glycation endpoints (AGEs) by supporting autophagy (these AGEs make skin thinner and more fragile)
• Decreases inflammation from fat cells
• Improve mitochondrial dysfunction seen in aging skin
• Anti-inflammatory effects by modulating your immune system

#3 NAD Supports Healthy Aging

NAD+ supports healthy aging in multiple ways:

• Counteracts age-related metabolic decline (related to decreased sirtuin activity)
• Compensates for age-related mitochondrial dysfunction (mediated by CD38)
• Supporting the "longevity network" communication between the hypothalamus, skeletal muscle, and adipose tissue
• May reverse skeletal muscle aging
• Protect heart muscle from heart disease
• Can improve neuron survival in age-related cognitive conditions
• Preserving genomic stability by supporting DNA repair

It is believed that NAD+ deficiency actually accelerates aging. These benefits in aging are in addition to its improvements in improving the quality of life.

#4 Cardiovascular Performance is Reinforced by NAD

NAD+ promotes cardiovascular performance through several key pathways:

• Supporting insulin sensitivity
• Heart pumping function
• Improve exercise capacity
• Counteract harmful effects of the Western Diet

In fact, NAD+ levels decrease with higher blood pressure and obesity.

#5 Detoxification from Alcohol and Toxins Requires NAD

Your body is exposed to toxins everyday, including:

• Dietary toxins
• Environmental pollutants
• Water and air-borne toxins
• Healing from infection

Detoxification requires support for oxidation, DNA repair, redox homeostasis, optimized metabolism. NAD+ is central to many of these functions. In particular:

• Metabolism of alcohol
• Balancing oxidative stress with anti-oxidant support (called redox homeostasis)
• Support for anti-oxidation via Sirtuin signaling
• DNA repair
• Supporting relief form long COVID

Learn More About NAD+ for Your Health

NAD+ has numerous impacts on your body. You can read recent reviews in Nature and the American Heart Association journals. Contact Clarus Health to learn more about BR+ certified NAD+ therapy in the San Francisco Bay Area.