*The FDA has not approved intravenous ketamine or NAD+ for the treatment of any psychiatric or pain condition. These articles reference off-label use. Like all medical treatments, the discussed therapies carry risks and benefits. Speak with a doctor at Clarus Health to learn if these therapies may be right for you.
Ketamine and NAD are powerful therapies for chronic pain that has been resistant to standard treatments and medications
Ketamine & NAD are revolutionary therapies to treat the root causes of chronic pain for more successful treatment with fewer side effects
Dr. Kaveh’s holistic chronic pain treatment addresses the root causes of pain, including both physical and psychological. The sources of pain include:
Undertreated pain from any of these sources can have serious health consequences and pain absolutely requires thoughtful and compassionate treatment.
Chronic pain becomes debilitating from repeated experiences of pain throughout the body. This forms a “pain feedback loop” that makes the brain and spinal cord more sensitive to pain when the pain is not buffered. Buffering pain not only helps reduce the painful sensations but can also prevent the brain and spinal cord from becoming sensitized.
Many neurochemicals are involved in the transmission of painful signals, including glutamate. Ketamine directly affects glutamate and the NMDA receptor to change pain transmission and help “re-wire” painful nerve connections throughout the brain and spinal cord (called synaptogenesis).
NAD works together with Ketamine to further enhance the pain-relieving effects at the NMDA reception.
Depression and anxiety often occur with chronic pain. It may be a “chicken and egg” problem because chronic pain can cause depression and anxiety, but chronic pain can also be worsened by depression and anxiety. This is especially true in chronic fatigue syndrome or myalgic encephalomyelitis.
This tight linkage between pain, depression, anxiety, and trauma means that treating any one of these connections requires also treating other co-existing conditions. Ketamine and NAD can not only address the neurochemical imbalances (and here) in these conditions but also soften the cognitive rigidity that exacerbates these conditions.
The Stellate Ganglion Block (SGB) is an effective technique to reduce nerve-related pain, such as complex regional pain syndrome (CRPS), formerly called reflex sympathetic dystrophy (RSD). It is also effective in reducing symptoms of anxiety, irritability, PTSD, hot flashes, heart rhythm problems, and long COVID symptoms. The SGB reduces the fight-flight response, also known as the sympathetic nervous system. Some pain conditions are related to an overactive sympathetic nervous system. "Blocking" this fight-flight response, therefore, can significantly relieve such pain. SGB is very safe and has well-characterized side effects.
The opioid epidemic has demonstrated the risks of treating chronic pain from a “pill pushing” approach. While opioid medications can have a role in chronic pain treatment, they should be used holistically to minimize risks and side effects.
Ketamine and NAD are powerful treatments for chronic pain that can reduce the need for, and risks of, opioid pain medications. This helps better treat the underlying causes of chronic pain and reduce the associated risks of “undertreated” or “overtreated” pain, including cognitive deficits or mind-fog.
The cycles of pain throughout the spinal cord and brain are exhausting to the mind and body. These loops can also worsen depression and anxiety by increasing our cognitive rigidity as we “harden” our judgments of ourselves and others.
Ketamine therapy, especially with compassionate inquiry, can break this rigid behavioral cycle. Ketamine can “soften” the loops that our neurons are “stuck” in by forming new neural connections, a process called neuroplasticity. This “re-wiring” of the brain and spinal cord is a key part of healing from chronic pain both physically and psychologically.
Dr. Kaveh’s holistic approach to treating the root causes of chronic pain includes the following 3 steps:
Contact Clarus with any questions about how IV Ketamine therapy can help treat the root causes of your depression.