IV NAD+ and NR Therapy in San Francisco
NAD+ — nicotinamide adenine dinucleotide — is the coenzyme at the center of every energy-producing reaction in your body. It supports mitochondrial function, DNA repair, and the cellular processes that keep you feeling sharp and energized. The problem is that NAD+ levels decline significantly with age, chronic stress, poor sleep, and illness — and oral supplementation replaces only a fraction of what's lost. At Clarus Health, we deliver NAD+ intravenously, bypassing the gut entirely for direct cellular delivery — which is why many patients notice a difference within 24 hours of their first infusion.
The Bay Area's Only BR+ Certified Niagen Provider
Not all NAD+ is the same. Clarus Health is the San Francisco Bay Area's only BR+ certified clinic and premium Niagen provider — a distinction that matters for both safety and quality. Niagen (nicotinamide riboside, or NR) is among the most studied NAD+ precursors, with over 1,500 peer-reviewed publications examining its role in cellular energy metabolism, inflammation, and aging. Generic NAD+ formulations used at most IV clinics vary widely in purity and potency. BR+ certification means our protocols, dosing, and clinical oversight meet rigorous published standards for NAD+ administration — something no mobile IV drip service or wellness spa can claim.
NAD+ for Brain Fog and Mental Clarity
Brain fog is one of the most common — and most disabling — symptoms we see at Clarus Health. When the brain's energy supply is compromised, cognitive function suffers: slower processing, difficulty concentrating, word retrieval problems, and a persistent mental haze that sleep doesn't fix. Research and clinical experience suggest that IV NAD+ may support the neuronal energy supply underlying clear thinking by supporting the mitochondrial function that keeps neurons operating efficiently. Many patients describe the experience as lifting a weight from their mind — not stimulation, but restoration. NAD+ is not FDA-approved for the treatment of any condition, and individual results vary.
NAD+ for Chronic Fatigue and Long COVID
Chronic fatigue — whether from ME/CFS, post-viral illness, or Long COVID — is increasingly studied as a mitochondrial problem. Emerging research has identified NAD+ depletion as a potential contributing mechanism in Long COVID, and a 2025 randomized trial found that NR supplementation increased NAD+ levels and was associated with self-reported improvements in fatigue, sleep, and mood in some long COVID patients — though larger studies are still needed. IV delivery ensures that cells receive NAD+ directly, without the absorption limitations of oral forms. As with all treatments at Clarus Health, protocols are individualized and discussed thoroughly before any infusion begins.
NAD+ for Depression and Mood
The relationship between NAD+ and mood is an active area of research. NAD+ plays a role in neurotransmitter synthesis and mitochondrial health — both of which are implicated in depression and anxiety. Early research has explored NAD+ as a potential factor in mood regulation, though robust human clinical evidence is still developing. At Clarus Health, NAD+ is sometimes used alongside IV Ketamine or Spravato as part of a broader protocol — a conversation your physician will guide based on your specific history and goals.
If brain fog, fatigue, or low mood have been affecting your quality of life and conventional approaches haven't provided lasting relief, a free consultation with Dr. Kaveh is where we start exploring what may be driving your symptoms.
